The Research Partner for Products That Can't Use the Standard Playbook
IRB-approved study design. Publication-ready data. Built for categories where traditional clinical trials and insurance claims data don't reach — tobacco and nicotine, telehealth, compounding pharmacy, behavioral health, and regulated natural products.
Penzai · The real-world evidence infrastructure behind every MoreBetter study.
We didn't adapt a survey tool. We built Penzai from the ground up for longitudinal real-world evidence — the same participants, day after day, generating the kind of data that snapshot polls and one-time clinical trials can't reach.
Empirical AI, ethically built.
Most AI in healthcare predicts outcomes from molecular structure or insurance claims. Ours learns from real human responses — mapped to formulation profile, dose, and individual factors. We're building the empirical AI layer of real-world evidence: a model that gets smarter every quarter as the dataset grows, designed first for the categories that need it most and built to scale across every product category that deserves better data.
What We Build Evidence For
Four research programs, one underlying platform. Whether you're preparing for reimbursement, generating brand-level evidence, sharpening category positioning, or running ongoing consumer pulses — Penzai powers it all.
Real-World Evidence for Reimbursement
Generate the data your products will need to qualify for ACO, EOM, and emerging Medicaid frameworks. Our protocols capture the five core data domains — baseline, product exposure, outcomes, safety, and substitution — that reimbursement programs require. Brands collecting now position ahead of the regulatory wave.
Longitudinal Evidence Studies
Brand-level longitudinal studies on the Penzai platform. Same participants, daily data, structurally validated outcomes — designed once and used wherever the data needs to go: marketing claims, R&D decisions, peer-reviewed publication, or regulatory submission. From 30-day consumer studies to multi-year IRB-approved clinical research, the same infrastructure powers it all.
Competitive Benchmarking
See how your product performs against every major brand in your category. Real-world data on outcomes, repurchase intent, side effects, and consumer preference — measured across the same longitudinal participants, not snapshot polls.
Functional Consumer Insights
Six pulse surveys per year to our 25,000+ participant panel. Brands shape the questions; participants deliver structurally validated responses that academic and regulatory audiences trust. Annual subscription.
Trusted by brands and researchers who need data that holds up.
Participating in this study allows us to stay at the forefront of innovation while helping to shape standards that prioritize safety, quality, and consumer education. We're thrilled to sponsor this study and contribute to groundbreaking research in this rapidly evolving industry.

We partnered with MoreBetter to gather valuable insights related to product efficacy, published those results, got more traffic to the site, and converted that traffic better than we had been doing without their data. +1 for RWD.

MoreBetter's software is intuitive, powerful, and perfectly tailored for anyone looking to track real world data to gain insights into their formulations and products. The ability to customize and monitor individual responses for different treatments has been invaluable.

Where our research lives.
Peer-reviewed publications across leading medical journals, developed in partnership with university research teams since 2018.
From protocol to publishable evidence, in four steps.
Ready to generate evidence that holds up?
Start the conversation and we'll scope a study built for the data your business actually needs — whether that's marketing claims, regulatory submission, or peer-reviewed publication.
Request a Research Consultation